4-Bromo-3-oxo-butyric acid ethyl ester
Ethyl 4-bromoacetoacetate
CAS: 13176-46-0
Molecular Formula: C6H9BrO3
4-Bromo-3-oxo-butyric acid ethyl ester - Names and Identifiers
| Name | Ethyl 4-bromoacetoacetate |
| Synonyms | Ethyl 4-Vromoacetoacetate Ethyl 4-bromoacetoacetate Ethyl-4-brom-3-oxobutanoat 4-broMo ethyl acetoacetate Ethyl 4-bromo-3-oxobutanoate 4-Bromo-3-oxobutanoic acid Et ester 4-BroMoacetoacetic acid ethyl ester 4-Bromo-3-oxo-butyric acid ethyl ester 4-BroMo-3-oxo-butyric acid Methyl ester Butanoic acid, 4-bromo-3-oxo-, ethyl ester |
| CAS | 13176-46-0 |
| EINECS | 806-757-0 |
| InChI | InChI=1/C6H9BrO3/c1-2-10-6(9)3-5(8)4-7/h2-4H2,1H3 |
4-Bromo-3-oxo-butyric acid ethyl ester - Physico-chemical Properties
| Molecular Formula | C6H9BrO3 |
| Molar Mass | 209.04 |
| Density | 1.511 |
| Boling Point | 231.6 °C |
| Flash Point | 93.9°C |
| Vapor Presure | 0.0616mmHg at 25°C |
| pKa | 9.56±0.46(Predicted) |
| Storage Condition | 2-8°C(protect from light) |
| Refractive Index | 1.5281 (estimate) |
| Physical and Chemical Properties | Density 1.511(28 °c) 1.528(18 °c), boiling point 115-116 °c/15mmHg. |
4-Bromo-3-oxo-butyric acid ethyl ester - Risk and Safety
| Hazard Symbols | F - Flammable |
4-Bromo-3-oxo-butyric acid ethyl ester - Introduction
Ethyl 4-bromoacetoacetate is an organic compound with the formula C6H9BrO3. The following is an introduction to its nature, use, preparation and safety information:
Nature:
-Appearance: colorless liquid
-Density: approx. 1.50g/cm³
-Melting point: about 15-20 ℃
-Boiling point: about 145-150 ℃
-Solubility: Can be dissolved in organic solvents, such as ethanol and ether
Use:
-4-bromoethyl acetoacetate is mainly used in the field of organic synthesis, as an important intermediate to prepare a variety of compounds. It can participate in esterification reaction, substitution reaction and condensation reaction, etc. In the field of medicine, it may be used to synthesize certain drugs.
Preparation Method:
-The preparation of ethyl 4-bromoacetoacetate is generally carried out by chemical synthesis. A common preparation method is to react bromoacetoacetic acid with absolute ethanol under acidic conditions to obtain the product.
Safety Information:
-Ethyl 4-bromoacetoacetate is a chemical and should be used in accordance with safe operating procedures.
-It may be harmful to the human body and can enter the body through inhalation, ingestion or skin contact. Therefore, appropriate personal protective equipment such as goggles, gloves and protective clothing should be worn during use.
-When storing and handling, it should be stored in a closed container, away from fire and oxidizing agents.
-When disposing of waste, local regulations should be observed and safety measures should be taken to avoid harm to the environment.
Nature:
-Appearance: colorless liquid
-Density: approx. 1.50g/cm³
-Melting point: about 15-20 ℃
-Boiling point: about 145-150 ℃
-Solubility: Can be dissolved in organic solvents, such as ethanol and ether
Use:
-4-bromoethyl acetoacetate is mainly used in the field of organic synthesis, as an important intermediate to prepare a variety of compounds. It can participate in esterification reaction, substitution reaction and condensation reaction, etc. In the field of medicine, it may be used to synthesize certain drugs.
Preparation Method:
-The preparation of ethyl 4-bromoacetoacetate is generally carried out by chemical synthesis. A common preparation method is to react bromoacetoacetic acid with absolute ethanol under acidic conditions to obtain the product.
Safety Information:
-Ethyl 4-bromoacetoacetate is a chemical and should be used in accordance with safe operating procedures.
-It may be harmful to the human body and can enter the body through inhalation, ingestion or skin contact. Therefore, appropriate personal protective equipment such as goggles, gloves and protective clothing should be worn during use.
-When storing and handling, it should be stored in a closed container, away from fire and oxidizing agents.
-When disposing of waste, local regulations should be observed and safety measures should be taken to avoid harm to the environment.
Last Update：2024-04-09 20:48:19
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